SCHEMBL42993

SCHEMBL42993

NC(Cc1cccc(Cl)c1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 5/20 0.65
PTGS1 P23219 2/20 0.65
ALPI P09923 1/20 0.65
PKM P14618 1/20 0.65
XIAP P98170 1/20 0.65
NOS3 P29474 3/20 0.63
NOS1 P29475 3/20 0.63
NOS2 P35228 3/20 0.63
PNMT P11086 1/20 0.61
GRIA2 P42262 1/20 0.60
KIF11 P52732 1/20 0.56
KDM4E B2RXH2 1/20 0.56
USP2 O75604 1/20 0.56
EGFR P00533 1/20 0.56
LCK P06239 1/20 0.56
FYN P06241 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
ALOX15 P16050 1/20 0.56
HTR2A P28223 1/20 0.56
PTGS2 P35354 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29353281 1.00 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL298829 1.00 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL42994 1.00 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL30046991 1.00 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL27547066 0.98 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL27461719 0.98 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL27461718 0.98 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL28419408 0.97 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL7853137 0.89 SLC7A5 (0.55) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL2314258 0.87 SLC7A5 (0.77) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2326 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS BICYCLE TX LTD (GB) 2025-10-23 US claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
WO-2025128149-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-19 WO claimed
US-20250186630-A1 FIBROBLAST ACTIVATION PROTEIN TARGETING PEPTIDES VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-12 US claimed
CN-120081924-A GLP-1R receptor agonistic polypeptide compounds and uses thereof 中国药科大学 2025-06-03 CN claimed
CN-119390784-A Dual-agonism polypeptide compound and medical application thereof 中国药科大学 2025-02-07 CN claimed
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 US claimed
US-12084476-B2 Tailored cyclodepsipeptides as potent non-covalent serine protease inhibitors Universität Duisburg-Essen (DE) 2024-09-10 US claimed
CN-118546214-A GLP-1R receptor agonistic polypeptide compounds and uses thereof 中国药科大学 2024-08-27 CN claimed
CN-118440155-A Dual-agonism polypeptide compound and medical application thereof 中国药科大学 2024-08-06 CN claimed
CN-1176102-A Use of nonpeptide bradykinin antagonists for treatment and prevention of chronic fibrogenetic liver disorders acute liver disorders and complications associated therewith HOECHST AG (DE) 1998-03-18 CN claimed
CN-1169992-A Sulfur-containing heterocyclic brad-ykinin antagcnists, process for their preparation and their use HOECHST AG (DE) 1998-01-14 CN claimed
EP-0808838-A1 Sulfur-containing heterocyclic bradykinin antagonists, processes for their production and use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-26 EP claimed
EP-0808627-A2 Use of non-peptide bradykinin antagonists for treating and preventing chronic fibrogenetic liver diseases, acute liver diseases and complications thereof HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-26 EP claimed
EP-0808628-A2 Use of non-peptide bradykinin antagonists for treating and preventing chronic fibrogenetic liver diseases, acute liver diseases and complications thereof HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-26 EP claimed
US-5648333-A POLYPEPTIDES FOR ANTIINFLAMMATORY AGENTS, WOUND HEALING AGENTS, ANTIALLERGENS OR CARDIOVASCULAR DISORDERS HOECHST AKTIENGESELLSCHAFT (DE) 1997-07-15 US claimed
EP-0370453-B1 Peptides having a Brady kinine-inhibiting activity HOECHST AG (DE) 1994-06-15 EP claimed
CN-1049505-A Peptide class with bradykinin antagonistic action HOECHST AG (DE) 1991-02-27 CN claimed
EP-0413277-A1 Peptide antagonists of bradykinin HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-20 EP claimed
EP-0370453-A2 Peptides having a Brady kinine-inhibiting activity HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed