Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.75 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.75 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.75 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.75 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.75 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302682 | 0.86 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL29807957 | 0.86 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| Hydrochloric Acid SCHEMBL28919738 | 0.85 | PIK3CD (0.98) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL4294332 | 0.84 | PIK3CD (0.64) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL3711633 | 0.79 | PIK3CD (0.84) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL3758328 | 0.79 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL3761617 | 0.77 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL28456454 | 0.75 | PIK3CG (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL12765132 | 0.74 | PIK3CG (0.70) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 | |
| SCHEMBL22230492 | 0.74 | PIK3CD (0.66) | PIK3CDPIK3CGPIK3CAPIK3CBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306126-A1 | Indole Derivatives | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306126-A1 | Indole Derivatives | MTOR, IDO1, AKT1S1 | PIK3CD 17/4885PIK3CG 32/4885PIK3CA 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.