SCHEMBL4299524

SCHEMBL4299524

CCCCCC(C=Cc1ccccc1)CCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.38
HDAC3 O15379 3/20 0.38
HDAC4 P56524 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC7 Q8WUI4 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC10 Q969S8 2/20 0.38
HDAC11 Q96DB2 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
HDAC9 Q9UKV0 2/20 0.38
HDAC5 Q9UQL6 2/20 0.38
TDP1 Q9NUW8 2/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CSNK1E P49674 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10703015 0.98 EGFR (0.43) EGFRMEN1KMT2ALMNAHDAC3
SCHEMBL236417 0.98 EGFR (0.43) EGFRMEN1KMT2ALMNAHDAC3
SCHEMBL4612716 0.98 EGFR (0.43) EGFRMEN1KMT2ALMNAHDAC3
SCHEMBL489041 0.95 HDAC3 (0.41) EGFRMEN1KMT2ALMNAHDAC3
Ethylene Glycol SCHEMBL4570274 0.94 EGFR (0.40) EGFRMEN1KMT2ALMNAHDAC3
SCHEMBL489091 0.90 MEN1 (0.43) EGFRMEN1KMT2ALMNAHDAC3
SCHEMBL9620000 0.90 MEN1 (0.43) EGFRMEN1KMT2ALMNAHDAC3
SCHEMBL488956 0.84 MEN1 (0.46) MEN1KMT2ALMNAHDAC3HDAC4
SCHEMBL11346885 0.84 EGFR (0.47) EGFRLMNAHDAC3HDAC4HDAC1
SCHEMBL27511144 0.83 MEN1 (0.41) EGFRMEN1KMT2ALMNAHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090267489-A1 GAS BARRIER THIN FILM LAMINATE, GAS BARRIER RESIN SUBSTRATE AND ORGANIC EL DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-10-29 US disclosed
US-20090226832-A1 TONER OF STATIC CHARGE IMAGE AND METHOD FOR MANUFACTURING THE SAME HUBEI DINGLONG CHEMICAL CO., LTD. (CN) 2009-09-10 US disclosed
EP-0768862-B1 PERSONAL CARE COMPOSITIONS CONTAINING THERMOPLASTIC ELASTOMERIC GRAFT COPOLYMERS PROCTER & GAMBLE (US) 2001-10-17 EP disclosed
US-6165455-A Personal care compositions containing thermoplastic elastomeric graft copolymers THE PROCTER & GAMBLE COMPANY (US) 2000-12-26 US disclosed
US-6136896-A Graft copolymers containing polydiorganosiloxane and polybutylene grafts DOW CORNING CORPORATION (US) 2000-10-24 US disclosed
EP-1013682-A1 Graft copolymers containing polydiorganosiloxane and polybutylene grafts DOW CORNING CORPORATION (US) 2000-06-28 EP disclosed
EP-0768862-A1 PERSONAL CARE COMPOSITIONS CONTAINING THERMOPLASTIC ELASTOMERIC GRAFT COPOLYMERS THE PROCTER & GAMBLE COMPANY (US) 1997-04-23 EP disclosed
WO-1996000562-A1 PERSONAL CARE COMPOSITIONS CONTAINING THERMOPLASTIC ELASTOMERIC GRAFT COPOLYMERS THE PROCTER & GAMBLE COMPANY (US) 1996-01-11 WO disclosed
EP-0247776-B1 AQUEOUS-BASED SEALANT COMPOSITIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-12-16 EP disclosed
EP-0342812-A2 Photopolymerisable compositions suitable for recording holographic information IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-11-23 EP disclosed
US-4806590-A VINYLIDENE CHLORIDE COPOLYMER AND FILLER IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-02-21 US disclosed
EP-0247776-A2 Aqueous-based sealant compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-12-02 EP disclosed