Betaine

Betaine

SCHEMBL4300224

C=C[n+]1ccccc1.C[N+](C)(C)CC(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

BHMTBHMT2

The experimentally established mechanism targets of Betaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
APEX1 P27695 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Betaine SCHEMBL3642873 0.78 TSHR (0.56) TSHRALDH1A1LMNAAPEX1
Betaine SCHEMBL399905 0.73 TSHR (1.00) TSHRALDH1A1LMNAAPEX1
Betaine SCHEMBL134333 0.73
Acetic Acid SCHEMBL5610717 0.73 CA1 (0.38) ALDH1A1
Betaine SCHEMBL3179196 0.72 TSHR (0.52) TSHRALDH1A1LMNAAPEX1
Betaine SCHEMBL4654474 0.72 TSHR (0.42) TSHRALDH1A1LMNAAPEX1
Betaine SCHEMBL16046840 0.71
Betaine SCHEMBL1312998 0.71
Betaine SCHEMBL912129 0.71
Betaine SCHEMBL1318276 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024068552-A1 POROUS METAL PLATE MATERIAL VECO B.V. (NL) 2024-04-04 WO disclosed
EP-2665794-A1 FAMILIES OF SCALE-INHIBITORS HAVING DIFFERENT ABSORPTION PROFILES AND THEIR APPLICATION IN OILFIELD Rhodia Operations (FR) 2013-11-27 EP disclosed
CN-102174777-B Method of using aldehyde-functionalized polymers to enhance paper machine dewatering NALCO CO 2013-03-06 CN disclosed
WO-2012098186-A1 FAMILIES OF SCALE-INHIBITORS HAVING DIFFERENT ABSORPTION PROFILES AND THEIR APPLICATION IN OILFIELD RHODIA OPERATIONS (FR) 2012-07-26 WO disclosed
CN-102174777-A Method of using aldehyde-functionalized polymers to enhance paper machine dewatering NALCO CO 2011-09-07 CN disclosed
WO-2009131881-A2 COMPOSITIONS AND METHODS FOR DIVERTING INJECTED FLUIDS TO ACHIEVE IMPROVED HYDROCARBON FLUID RECOVERY NALCO COMPANY (US) 2009-10-29 WO disclosed
CN-1914375-A Method of using aldehyde-functionalized polymers to enhance dewatering in papermaking machines NALCO CO (US) 2007-02-14 CN disclosed
US-RE39450-E1 Polyvinylpyrridinium derivatives as anti-dye transfer agents NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CO (US) 2006-12-26 US disclosed
EP-1167504-B1 Polyvinylpyrridinium derivatives as anti-dye transfer agents NAT STARCH CHEM INVEST (US) 2004-10-06 EP disclosed
EP-1167504-A1 Polyvinylpyrridinium derivatives as anti-dye transfer agents National Starch and Chemical Investment Holding Corporation (US) 2002-01-02 EP disclosed
US-6191098-B1 ANIOINIC SURFACTANTS AND AMPHOTERIC SURFACTANTS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2001-02-20 US disclosed
WO-1996035760-A1 BLEED RESISTANT CYANATE ESTER-CONTAINING COMPOSITIONS QUANTUM MATERIALS, INC. (US) 1996-11-14 WO disclosed
EP-0339909-A2 Anti-fogging resin film-forming composition NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-11-02 EP disclosed