Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464281 | 0.86 | HTR2C (0.52) | HTR2CPARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6000873 | 0.86 | HTR2C (0.52) | HTR2CPARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL873281 | 0.86 | HTR2C (0.52) | HTR2CPARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31107806 | 0.85 | HTR2C (0.51) | HTR2CPARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15122671 | 0.85 | HTR2C (0.51) | HTR2CPARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15122669 | 0.85 | HTR2C (0.51) | HTR2CPARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5083077 | 0.84 | HTR2C (0.51) | HTR2CPARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5083074 | 0.84 | HTR2C (0.51) | HTR2CPARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6691930 | 0.81 | HTR2C (0.48) | HTR2CPARP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14814214 | 0.81 | HTR2C (0.48) | HTR2CPARP1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038412-A2 | BETA-SECRETASE INHIBITING COMPOUNDS | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |