Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 6/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.43 |
| ▸ | CDC25B | P30305 | 6/20 | 0.43 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171027 | 1.00 | SELP (0.51) | SELPPTPN1CDC25BTACR2ENPP2 | |
| SCHEMBL1170785 | 0.90 | SELP (0.56) | SELPFAAH | |
| SCHEMBL1170783 | 0.90 | SELP (0.56) | SELPFAAH | |
| SCHEMBL1170786 | 0.90 | SELP (0.56) | SELPFAAH | |
| SCHEMBL1170905 | 0.90 | SELP (0.58) | SELPFAAH | |
| SCHEMBL1170902 | 0.90 | SELP (0.58) | SELPFAAH | |
| SCHEMBL1170900 | 0.90 | SELP (0.58) | SELPFAAH | |
| SCHEMBL1170806 | 0.89 | SELP (0.53) | SELPFAAH | |
| SCHEMBL1170807 | 0.89 | SELP (0.53) | SELPFAAH | |
| SCHEMBL1170808 | 0.89 | SELP (0.53) | SELPFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047249-A9 | ALPHA-GALACTOCERAMIDE ANALOGS, THEIR METHODS OF MANUFACTURE, INTERMEDIATE COMPOUNDS USEFUL IN THESE METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-12-23 | — | — | WO | disclosed |
| EP-2099813-A2 | ALPHA-GALACTOCERAMIDE ANALOGS, THEIR METHODS OF MANUFACTURE, INTERMEDIATE COMPOUNDS USEFUL IN THESE METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Centre National de la Recherche Scientifique (FR) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008047249-A2 | ALPHA-GALACTOCERAMIDE ANALOGS, THEIR METHODS OF MANUFACTURE, INTERMEDIATE COMPOUNDS USEFUL IN THESE METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-04-24 | — | — | WO | disclosed |