Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.70 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723304 | 0.92 | PIK3CD (0.68) | PIK3CDPIK3CGMAPT | |
| SCHEMBL4289089 | 0.90 | PIK3CD (0.65) | PIK3CDPIK3CGMAPTSLC40A1 | |
| SCHEMBL4291785 | 0.89 | PIK3CD (0.64) | PIK3CDPIK3CGMAPTSLC40A1 | |
| SCHEMBL4287828 | 0.88 | PIK3CD (0.62) | PIK3CDPIK3CGMAPT | |
| SCHEMBL2303352 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3CGMAPT | |
| SCHEMBL4288292 | 0.82 | PIK3CG (0.59) | PIK3CDPIK3CGMAPT | |
| SCHEMBL2722971 | 0.82 | PIK3CG (0.57) | PIK3CDPIK3CGMAPT | |
| SCHEMBL4292331 | 0.81 | PIK3CD (0.53) | PIK3CDPIK3CGMAPT | |
| SCHEMBL4288631 | 0.80 | PIK3CG (0.59) | PIK3CDPIK3CGMAPT | |
| SCHEMBL2302991 | 0.79 | PIK3CD (0.82) | PIK3CDPIK3CGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052102-A1 | QUINOXALINE DERIVATES | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |