Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311692 | 1.00 | F2 (0.50) | F2KLKB1PRSS1PRSS2PRSS3 | |
| SCHEMBL4308027 | 0.86 | F2 (0.51) | F2KLKB1 | |
| SCHEMBL4306897 | 0.86 | F2 (0.51) | F2KLKB1 | |
| SCHEMBL4308363 | 0.84 | F2 (0.44) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4313165 | 0.83 | F2 (0.50) | F2KLKB1PRSS1PRSS2PRSS3 | |
| SCHEMBL3154741 | 0.79 | F2 (0.58) | F2KLKB1 | |
| SCHEMBL3149590 | 0.79 | F2 (0.58) | F2KLKB1 | |
| SCHEMBL1432496 | 0.79 | F2 (0.44) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4310677 | 0.79 | F2 (0.53) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4308746 | 0.77 | NAMPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |