⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL89324 | 0.53 | — | — | |
| SCHEMBL20719507 | 0.50 | — | — | |
| SCHEMBL940079 | 0.48 | — | — | |
| SCHEMBL12172386 | 0.45 | — | — | |
| SCHEMBL12172388 | 0.45 | — | — | |
| Ethylene Thiourea SCHEMBL41176 | 0.45 | — | — | |
| SCHEMBL5241396 | 0.40 | — | — | |
| Hydrochloric Acid SCHEMBL9573677 | 0.35 | — | — | |
| Hydrochloric Acid SCHEMBL9104923 | 0.35 | — | — | |
| Hydrochloric Acid SCHEMBL72335 | 0.35 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597423-B1 | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO (JP) | 2002-03-06 | — | — | EP | claimed |
| EP-0582291-B1 | Process for preparing carbapenem derivatives | TANABE SEIYAKU CO (JP) | 1997-11-05 | — | — | EP | claimed |
| US-5359059-A | Cyclization of azetidinone compound with base and silylating agent | TANABE SEIYAKU CO., LTD. (JP) | 1994-10-25 | — | — | US | claimed |
| EP-0597423-A2 | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-18 | — | — | EP | claimed |
| EP-0582291-A1 | Process for preparing carbapenem derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1994-02-09 | — | — | EP | claimed |
| US-8507546-B2 | Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases | INSTITUTO DE MEDICINA MOLECULAR, FACULDADE DE MEDICINA DA UNIVERSIDADE DE LISBOA (PT) | 2013-08-13 | — | — | US | disclosed |
| US-20120276121-A1 | USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES | INSTITUTO DE MEDICINA MOLECULAR, FACULDADE DE MEDICINA DA UNIVERSIDADE DE LISBOA (PT) | 2012-11-01 | — | — | US | disclosed |
| US-20090324580-A1 | Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases | CENIX BIOSCIENCE GMBH (DE) | 2009-12-31 | — | — | US | disclosed |
| EP-1991215-A1 | USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES | Cenix Bioscience GmbH (DE) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007101710-A1 | USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES | CENIX BIOSCIENCE GMBH (DE) | 2007-09-13 | — | — | WO | disclosed |
| EP-0913151-B1 | ANTI-HELICOBACTER PYLORI COMPOSITIONS CONTAINING 1-METHYLCARBAPENEM DERIVATIVES AS THE ACTIVE INGREDIENT | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6180621-B1 | ADMINISTERING TO WARM-BLOODED ANIMALS FOR TREATMENT AND PREVENTION OF INFECTIOUS DISEASES CAUSED BY HELICOBACTER PYLORI | SANKYO COMPANY, LIMITED (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0913151-A1 | ANTI-HELICOBACTER PYLORI COMPOSITIONS CONTAINING 1-METHYLCARBAPENEM DERIVATIVES AS THE ACTIVE INGREDIENT | Sankyo Company, Limited (JP) | 1999-05-06 | — | — | EP | disclosed |
| EP-0474243-B1 | 1-Methylcarbapenem derivatives and process for preparation thereof | TANABE SEIYAKU CO (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5208348-A | Intermediates for thienamycin derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1993-05-04 | — | — | US | disclosed |
| US-5153187-A | Microbiocides having stability against dehydropeptidase and high absorrbability by oral administration | TANABE SEIYAKU CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0474243-A1 | 1-Methylcarbapenem derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-03-11 | — | — | EP | disclosed |