Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453520 | 1.00 | AVPR1B (0.79) | AVPR1B | |
| SCHEMBL4306433 | 0.95 | AVPR1B (0.76) | AVPR1B | |
| SCHEMBL4307515 | 0.88 | AVPR1B (1.00) | AVPR1B | |
| SCHEMBL4308551 | 0.88 | AVPR1B (0.81) | AVPR1B | |
| Hydrochloric Acid SCHEMBL4311787 | 0.87 | AVPR1B (0.80) | AVPR1B | |
| SCHEMBL4311840 | 0.87 | AVPR1B (0.80) | AVPR1B | |
| Hydrochloric Acid SCHEMBL4307146 | 0.86 | AVPR1B (0.79) | AVPR1B | |
| SCHEMBL4308801 | 0.86 | AVPR1B (0.79) | AVPR1B | |
| Hydrochloric Acid SCHEMBL4302724 | 0.85 | AVPR1B (0.78) | AVPR1B | |
| SCHEMBL4446702 | 0.85 | AVPR1B (0.77) | AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009130231-A1 | PYRROLO [1, 2-A] PYRAZINE DERIVATIVES AS VASOPRESSIN VIB RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | WO | claimed |
| WO-2009130231-A1 | PYRROLO [1, 2-A] PYRAZINE DERIVATIVES AS VASOPRESSIN VIB RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009130231-A1 | PYRROLO [1, 2-A] PYRAZINE DERIVATIVES AS VASOPRESSIN VIB RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | WO | disclosed |