Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 12/20 | 1.00 |
| ▸ | PTGER3 | P43115 | 6/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.70 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.70 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.65 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.65 |
| ▸ | PTGIR | P43119 | 2/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | MGLL | Q99685 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303639 | 1.00 | PTGFR (1.00) | PTGFRPTGER3THRBMEN1KMT2A | |
| SCHEMBL3052474 | 0.90 | PTGFR (0.82) | PTGFRPTGER3THRBMEN1KMT2A | |
| SCHEMBL12928657 | 0.90 | PTGFR (0.82) | PTGFRPTGER3THRBMEN1KMT2A | |
| SCHEMBL3052476 | 0.90 | PTGFR (0.82) | PTGFRPTGER3THRBMEN1KMT2A | |
| SCHEMBL3052472 | 0.90 | PTGFR (0.82) | PTGFRPTGER3THRBMEN1KMT2A | |
| SCHEMBL3056284 | 0.88 | PTGFR (0.79) | PTGFRPTGER3THRBMEN1KMT2A | |
| SCHEMBL29392750 | 0.88 | PTGFR (0.79) | PTGFRPTGER3THRBMEN1KMT2A | |
| SCHEMBL3056281 | 0.88 | PTGFR (0.79) | PTGFRPTGER3THRBMEN1KMT2A | |
| SCHEMBL3056287 | 0.88 | PTGFR (0.79) | PTGFRPTGER3THRBMEN1KMT2A | |
| SCHEMBL11337829 | 0.88 | PTGFR (0.78) | PTGFRPTGER3THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084124-A1 | POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF PROSTAGLANDINS AND RELATED COMPOUNDS WITH VERY HIGH SKIN PENETRATION RATES | Techfields Biochem Co. Ltd. (CN) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008041054-A1 | POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF PROSTAGLANDINS AND RELATED COMPOUNDS WITH VERY HIGH SKIN PENETRATION RATES | TECHFIELDS BIOCHEM CO. LTD (CN) | 2008-04-10 | — | — | WO | disclosed |