SCHEMBL4303867

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13702621	0.87	AKT1 (0.52)	AKT1ROCK1RPS6KA1RPS6KA5AKT2
	SCHEMBL4288171	0.85	SLC2A1 (0.57)	SLC2A1AKT1ROCK1RPS6KA1RPS6KA5
	SCHEMBL4299426	0.84	AKT1 (0.69)	AKT1ROCK1RPS6KA1RPS6KA5AKT2
	SCHEMBL4299419	0.83	AKT1 (0.56)	SLC2A1AKT1ROCK1RPS6KA1RPS6KA5
	Trifluoroacetic Acid SCHEMBL4301625	0.79	AKT1 (0.71)	AKT1ROCK1RPS6KA1RPS6KA5AKT2
	SCHEMBL4301683	0.79	SLC2A1 (0.57)	SLC2A1AKT1ROCK1RPS6KA1RPS6KA5
	SCHEMBL4292488	0.79	SLC2A1 (0.59)	SLC2A1AKT1ROCK1RPS6KA1RPS6KA5
	SCHEMBL10053689	0.78	AKT1 (0.72)	SLC2A1AKT1ROCK1RPS6KA1RPS6KA5
	SCHEMBL21350454	0.78	AKT1 (0.73)	SLC2A1AKT1ROCK1RPS6KA1RPS6KA5
	SCHEMBL4302078	0.78	AKT1 (0.56)	SLC2A1AKT1ROCK1RPS6KA1RPS6KA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.