Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13663651 | 0.95 | AR (0.72) | ARHRH3 | |
| Trifluoroacetic Acid SCHEMBL4231073 | 0.92 | AR (0.61) | ARKDM1A | |
| Trifluoroacetic Acid SCHEMBL4228067 | 0.88 | AR (0.60) | AR | |
| SCHEMBL13663646 | 0.87 | AR (0.67) | ARKDM1A | |
| Trifluoroacetic Acid SCHEMBL4311130 | 0.86 | AR (0.74) | AR | |
| SCHEMBL4300798 | 0.85 | AR (0.75) | AR | |
| SCHEMBL4303905 | 0.85 | AR (0.75) | AR | |
| SCHEMBL4306475 | 0.85 | AR (0.75) | AR | |
| Trifluoroacetic Acid SCHEMBL4302663 | 0.83 | AR (0.70) | AR | |
| SCHEMBL4301336 | 0.83 | AR (0.80) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270361-A1 | Substituted pyrazole derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270361-A1 | Substituted pyrazole derivatives and use thereof | CBR3, CBR1, NOX5 | AR 622/4885HRH3 14/4885KDM1A 2318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.