⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388602 | 0.82 | — | — | |
| SCHEMBL10642973 | 0.71 | TP53 (0.37) | — | |
| SCHEMBL4393738 | 0.69 | — | — | |
| SCHEMBL30920011 | 0.69 | — | — | |
| SCHEMBL1299384 | 0.69 | — | — | |
| SCHEMBL11583571 | 0.69 | — | — | |
| SCHEMBL10643112 | 0.69 | — | — | |
| SCHEMBL6495064 | 0.69 | — | — | |
| SCHEMBL123648 | 0.68 | HPGD (0.34) | — | |
| SCHEMBL4619038 | 0.65 | OR51E2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321131-A1 | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT AND PREVENTION OF AN ANTINEOPLASTIC-INDUCED TOXICITY | NUVAMID SA (CH) | 2023-10-12 | — | — | US | claimed |
| EP-4192475-A1 | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT AND PREVENTION OF AN ANTINEOPLASTIC-INDUCED TOXICITY | Nuvamid SA (CH) | 2023-06-14 | — | — | EP | claimed |
| CN-109476668-B | 6, 7-dihydro-4H-pyrazolo [1,5-a ] pyrazines and 6, 7-dihydro-4H-triazolo [1,5-a ] pyrazines for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2022-03-22 | — | — | CN | claimed |
| EP-1200400-B1 | SUBSTITUTED PYRROLIDIN-2,3,4-TRION DERIVATIVES USEFUL AS NMDA-RECEPTOR ANTAGONISTS | GRUENENTHAL GMBH (DE) | 2004-09-29 | — | — | EP | claimed |
| US-6716872-B2 | USING THE COMPOUNDS FOR TREATING PAIN, ANXIETY AND VARIOUS OTHER DISEASES OR CONDITIONS. | GRUENENTHAL GMBH (DE) | 2004-04-06 | — | — | US | claimed |
| US-20030027852-A1 | Substituted pyrrolidine-2,3,4-trione 3-oxime deerivatives which are active as NMDA receptor antagonists | GRUENENTHAL GMBH (DE) | 2003-02-06 | — | — | US | claimed |
| CN-117137238-A | Contact lens packaging container and product thereof | 晶硕光学股份有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-114442431-B | Photosensitive resin composition containing polyimide precursor | 上海玟昕科技有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-108884470-B | HPPD variants and methods of use | 巴斯夫农业种子解决方案美国有限责任公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-109476668-B | 6, 7-dihydro-4H-pyrazolo [1,5-a ] pyrazines and 6, 7-dihydro-4H-triazolo [1,5-a ] pyrazines for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-105722830-B | Aryl thioethers derivative and aryl sulfoxid es derivative as acaricide and insecticide | 拜耳作物科学股份公司 | 2019-06-04 | — | — | CN | disclosed |
| US-9981928-B2 | Aryl sulfide derivatives and aryl sulfoxide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-29 | — | — | US | disclosed |
| CN-105722830-A | Aryl sulfide derivatives and aryl sulfoxide derivatives as acaricides and insecticides | 拜耳作物科学股份公司 | 2016-06-29 | — | — | CN | disclosed |
| US-5214051-A | Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed | PFIZER INC. (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0472153-A1 | A silver halide color photographic material | Fuji Photo Film Co., Ltd. (JP) | 1992-02-26 | — | — | EP | disclosed |
| US-5037834-A | Heterocycylic-substituted quinoline-carboxylic acids | PFIZER INC. (US) | 1991-08-06 | — | — | US | disclosed |
| WO-1989005643-A1 | HETEROCYCLIC-SUBSTITUTED QUINOLINE-CARBOXYLIC ACIDS | PFIZER INC. (US) | 1989-06-29 | — | — | WO | disclosed |
| EP-0321191-A2 | Heterocyclic-substituted quinoline-carboxylic acids | PFIZER INC. (US) | 1989-06-21 | — | — | EP | disclosed |
| US-3994916-A | DISPERSANTS IN WATERBASED PAINTS | IMC CHEMICAL GROUP, INC. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3994919-A | DISPERSANTS IN WATERBASED PAINTS | IMC CHEMICAL GROUP, INC. (US) | 1976-11-30 | — | — | US | disclosed |