Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | NPC1 | O15118 | 6/20 | 0.74 |
| ▸ | RAB9A | P51151 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | GAA | P10253 | 5/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | POLB | P06746 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | PKM | P14618 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.63 |
| ▸ | RELA | Q04206 | 4/20 | 0.63 |
| ▸ | GFER | P55789 | 2/20 | 0.63 |
| ▸ | MITF | O75030 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932581 | 0.89 | KDM4E (0.60) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9797066 | 0.85 | KDM4E (0.71) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14030811 | 0.85 | KDM4E (0.72) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4305667 | 0.82 | KDM4E (0.68) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21708400 | 0.79 | NPC1 (0.66) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5028038 | 0.79 | MAPT (0.64) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14157073 | 0.78 | APP (0.68) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9797268 | 0.77 | KDM4E (0.88) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8531346 | 0.77 | KDM4E (1.00) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8534417 | 0.77 | MAPT (0.79) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495106-B1 | O-aminophenol-containing AB-monomer for heterocyclic rigid-rod polymers | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-02-24 | — | — | US | claimed |
| US-7495106-B1 | O-aminophenol-containing AB-monomer for heterocyclic rigid-rod polymers | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-02-24 | — | — | US | disclosed |
| US-7495106-B1 | O-aminophenol-containing AB-monomer for heterocyclic rigid-rod polymers | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-02-24 | — | — | US | disclosed |
| US-7495106-B1 | O-aminophenol-containing AB-monomer for heterocyclic rigid-rod polymers | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2009-02-24 | — | — | US | disclosed |