SCHEMBL4305978

SCHEMBL4305978

Fc1nc2c(F)c(F)c(F)c(F)c2nc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16702660 0.84
SCHEMBL24070442 0.81
SCHEMBL2252282 0.80
SCHEMBL13197716 0.79
SCHEMBL12111359 0.78
SCHEMBL12340162 0.78
SCHEMBL4308426 0.74 KDM4E (0.33)
SCHEMBL24070448 0.69
SCHEMBL4311227 0.69 MEN1 (0.33)
SCHEMBL188694 0.67 MEN1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106905306-B Hexafluoro quinoxaline compounds and hexafluoro quinoxaline copolymer and application 中南大学 2019-07-12 CN claimed
CN-106905306-A Hexafluoro quinoxaline compounds and hexafluoro quinoxaline copolymer and application 中南大学 2017-06-30 CN claimed
US-20090221787-A1 Production Of Monomer, Oligomer And Polymer Phosphonic Acid Esters And Phosphonic And Sulphonic Acids By A Nucleophile Aromatic Substitution HARING THOMAS 2009-09-03 US claimed
EP-1931608-A1 PRODUCTION OF MONOMER, OLIGOMER AND POLYMER PHOSPHONIC ACID ESTERS AND PHOSPHONIC AND SULPHONIC ACIDS BY A NUCLEOPHILE AROMATIC SUBSTITUTION Universität Stuttgart (DE) 2008-06-18 EP claimed
WO-2007006300-A1 PRODUCTION OF MONOMER, OLIGOMER AND POLYMER PHOSPHONIC ACID ESTERS AND PHOSPHONIC AND SULPHONIC ACIDS BY A NUCLEOPHILE AROMATIC SUBSTITUTION Universität Stuttgart (DE) 2007-01-18 WO claimed
US-20190355908-A1 Organic Cocrystal and Applications of the Same HU WENPING (CN) 2019-11-21 US disclosed
CN-106905306-B Hexafluoro quinoxaline compounds and hexafluoro quinoxaline copolymer and application 中南大学 2019-07-12 CN disclosed
CN-106905306-B Hexafluoro quinoxaline compounds and hexafluoro quinoxaline copolymer and application 中南大学 2019-07-12 CN disclosed
CN-106905306-A Hexafluoro quinoxaline compounds and hexafluoro quinoxaline copolymer and application 中南大学 2017-06-30 CN disclosed
CN-106905306-A Hexafluoro quinoxaline compounds and hexafluoro quinoxaline copolymer and application 中南大学 2017-06-30 CN disclosed
WO-2006066569-A2 IONOMERS AND IONOMER BLENDS BASED ON PARTIALLY FLUORINATED POLY(HETERO)ARYLS HÄRING, Thomas (DE) 2006-06-29 WO disclosed