Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146591 | 1.00 | EPHX2 (0.78) | EPHX2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL5245759 | 0.94 | EPHX2 (0.79) | EPHX2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL5244399 | 0.93 | EPHX2 (0.77) | EPHX2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL5242567 | 0.93 | EPHX2 (0.77) | EPHX2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL5246442 | 0.93 | EPHX2 (0.77) | EPHX2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL612941 | 0.86 | EPHX2 (0.76) | EPHX2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL612942 | 0.86 | EPHX2 (0.76) | EPHX2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL4005679 | 0.81 | EPHX2 (0.76) | EPHX2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5246527 | 0.81 | KDM4E (0.72) | EPHX2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL5282637 | 0.80 | MEN1 (0.72) | EPHX2MEN1KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |