Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15107929 | 0.84 | SMN1; SMN2 (0.69) | BACE1SMN1; SMN2CYP1A2MAPTALDH1A1 | |
| SCHEMBL4809195 | 0.79 | BACE1 (1.00) | BACE1SMN1; SMN2CYP1A2MAPTALDH1A1 | |
| Propylthiouracil SCHEMBL4537771 | 0.79 | BACE1 (0.64) | BACE1SMN1; SMN2CYP1A2MAPTALDH1A1 | |
| SCHEMBL9414223 | 0.77 | BACE1 (0.60) | BACE1SMN1; SMN2CYP1A2MAPTALDH1A1 | |
| SCHEMBL2786194 | 0.77 | CYP1A2 (0.73) | BACE1SMN1; SMN2CYP1A2MAPTALDH1A1 | |
| SCHEMBL26063171 | 0.73 | CYP1A2 (0.77) | SMN1; SMN2CYP1A2MAPTALDH1A1NPSR1 | |
| SCHEMBL26064133 | 0.73 | CYP1A2 (0.68) | BACE1SMN1; SMN2CYP1A2MAPTALDH1A1 | |
| SCHEMBL1895087 | 0.72 | BACE1 (0.54) | BACE1SMN1; SMN2CYP1A2MAPTALDH1A1 | |
| SCHEMBL26039927 | 0.72 | CYP1A2 (0.75) | SMN1; SMN2CYP1A2MAPTALDH1A1NPSR1 | |
| SCHEMBL1892022 | 0.71 | HTT (0.67) | BACE1SMN1; SMN2CYP1A2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024103188-A1 | LIN28 INHIBITORS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-05-23 | — | — | WO | disclosed |
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |