SCHEMBL4306427

SCHEMBL4306427

CCCc1nc(C)n(-c2ccc(OC3CC3)cc2)c(=O)c1Cc1ccc(-c2ccccc2)c(-c2noc(=O)[nH]2)c1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC33A1 O00400 19/20 0.50
PPARG P37231 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2842927 0.97 SLC33A1 (0.49) SLC33A1
SCHEMBL1889422 0.92 SLC33A1 (0.58) SLC33A1
Hydrochloric Acid SCHEMBL1890378 0.91 SLC33A1 (0.58) SLC33A1
SCHEMBL1894517 0.91 SLC33A1 (0.58) SLC33A1
Bromide SCHEMBL3570529 0.91 SLC33A1 (0.57) SLC33A1
SCHEMBL1888914 0.90 SLC33A1 (0.56) SLC33A1
SCHEMBL3486931 0.90 SLC33A1 (0.47) SLC33A1PPARG
SCHEMBL12349372 0.90 SLC33A1 (0.56) SLC33A1
Hydrochloric Acid SCHEMBL1885834 0.89 SLC33A1 (0.55) SLC33A1
SCHEMBL1893670 0.89 SLC33A1 (0.55) SLC33A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009133970-A1 CRYSTALLINE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-11-05 WO disclosed