SCHEMBL430690

SCHEMBL430690

OC(Cc1ccccc1)Nc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
PSMB5 P28074 1/20 0.43
EPHX1 P07099 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TRPA1 O75762 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TAAR1 Q96RJ0 3/20 0.42
SLC18A2 Q05940 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41
PTGS1 P23219 1/20 0.41
XIAP P98170 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11810999 0.88 TRPV1 (0.43) TAAR1SIGMAR1SLC7A5MAOASLC6A2
SCHEMBL431573 0.87 HTT (0.50) CYP1A2PSMB5TRPA1CYP3A4CYP2C9
SCHEMBL10440174 0.81 EPHX1 (0.50) CYP1A2EPHX1TRPA1TAAR1SLC18A2
SCHEMBL3936936 0.77 CYP1A2 (0.46) CYP1A2EPHX1TRPA1TAAR1SLC18A2
SCHEMBL8200358 0.77 CA12 (0.48) EPHX1TDP1CYP3A4CA12CA9
SCHEMBL28127137 0.77 CYP1A2 (0.46) CYP1A2EPHX1TRPA1TAAR1SLC18A2
SCHEMBL27125297 0.77 EPHX1 (0.52) CYP1A2EPHX1TDP1CYP3A4CYP2D6
SCHEMBL474146 0.76 TAAR1 (0.59) CYP1A2EPHX1TRPA1CYP3A4CYP2D6
SCHEMBL2232457 0.76 TDP1 (0.44) CYP1A2TDP1CYP3A4CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL11785562 0.76 EPHX1 (0.50) CYP1A2EPHX1TDP1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8932980-B2 Ordered mesoporous titanosilicate and the process for the preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-01-13 US disclosed
EP-2595921-A1 ORDERED MESOPOROUS TITANOSILICATE AND THE PROCESS FOR THE PREPARATION THEREOF Council of Scientific & Industrial Research (IN) 2013-05-29 EP disclosed
US-20130116453-A1 ORDERED MESOPOROUS TITANOSILICATE AND THE PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-05-09 US disclosed
WO-2012011124-A1 ORDERED MESOPOROUS TITANOSILICATE AND THE PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-01-26 WO disclosed