SCHEMBL4307112

SCHEMBL4307112

CC(C)(C)C1N(C(=O)O)CC12CCNCC2

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18035056 0.90
SCHEMBL325510 0.85 CYP1A2 (0.33) CYP1A2
SCHEMBL21814085 0.83
SCHEMBL18812822 0.83 TSHR (0.36) CYP1A2
SCHEMBL29792262 0.81 ACACB (0.34)
SCHEMBL20512611 0.81
SCHEMBL19838077 0.80
SCHEMBL25408135 0.79
SCHEMBL18315516 0.75
SCHEMBL29792095 0.72 TSHR (0.35) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116472042-A 2-oxo-dihydroquinoline-3-carboxamide derivatives as modulators of GABA A type receptors 加的夫大学学院咨询有限公司 2023-07-21 CN disclosed
WO-2009130231-A1 PYRROLO [1, 2-A] PYRAZINE DERIVATIVES AS VASOPRESSIN VIB RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2009-10-29 WO disclosed