⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447726 | 0.82 | — | — | |
| SCHEMBL4447722 | 0.82 | — | — | |
| SCHEMBL5810631 | 0.81 | — | — | |
| SCHEMBL5810626 | 0.81 | — | — | |
| SCHEMBL4299892 | 0.77 | TLR7 (0.30) | — | |
| SCHEMBL4755190 | 0.72 | TLR7 (0.39) | — | |
| SCHEMBL4296147 | 0.70 | HPGD (0.38) | — | |
| SCHEMBL4300715 | 0.69 | TLR7 (0.34) | — | |
| SCHEMBL4298195 | 0.68 | TLR8 (0.33) | — | |
| SCHEMBL5806019 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270443-A1 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. | 2009-10-29 | — | — | US | disclosed |