Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | THPO | P40225 | 2/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | GABRA1 | P14867 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | GABRA2 | P47869 | 1/20 | 1.00 |
| ▸ | GABRB2 | P47870 | 1/20 | 1.00 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorambucil SCHEMBL5318105 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HIF1ALMNAMAPT | |
| Chlorambucil SCHEMBL28447772 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2ALDH1A1HIF1ALMNAMAPT | |
| Chlorambucil SCHEMBL28290938 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2ALDH1A1HIF1ALMNAMAPT | |
| Chlorambucil SCHEMBL27861200 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2ALDH1A1HIF1ALMNAMAPT | |
| Chlorambucil SCHEMBL11252839 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2ALDH1A1HIF1ALMNAMAPT | |
| Chlorambucil SCHEMBL23753952 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2ALDH1A1HIF1ALMNAMAPT | |
| Chlorambucil SCHEMBL28426894 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2ALDH1A1HIF1ALMNAMAPT | |
| Chlorambucil SCHEMBL4176516 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2ALDH1A1HIF1ALMNAMAPT | |
| Chlorambucil SCHEMBL5846926 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2ALDH1A1HIF1ALMNAMAPT | |
| Chlorambucil SCHEMBL28091318 | 0.98 | SMN1; SMN2 (0.97) | SMN1; SMN2ALDH1A1HIF1ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 184739 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607938-B1 | PHARMACEUTICAL COMPOSITION | SOVIC BRKICIC LJILJANA (HR) | 2026-05-27 | — | — | EP | claimed |
| EP-4748859-A2 | CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF | The Regents of the University of California (US) | 2026-05-27 | — | — | EP | claimed |
| CN-118489560-B | Method for breeding and updating germplasm resources of chlorambucil | INSTITUTE OF VEGETABLES AND FLOWERS CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122075497-A | Use of NLRP3 agonist for tumor treatment | — | 2026-05-26 | — | — | CN | claimed |
| CN-116209439-B | Cereblon protein modulators | Saint Jude Children's Research Hospital Ltd. (US) | 2026-05-26 | — | — | CN | claimed |
| US-20260137686-A1 | SOLID PHARMACEUTICAL FORMULATION OF PARP INHIBITORS AND USE THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2026-05-21 | — | — | US | claimed |
| US-20260139071-A1 | Subcutaneous Formulations Of Anti-CD38 Antibodies And Their Uses | JANSSEN BIOTECH INC (US) | 2026-05-21 | — | — | US | claimed |
| WO-2026102563-A1 | DISUBSTITUTED PYRIMIDOPYRROLE ANALOG AND USE THEREOF | 深圳湾实验室坪山生物医药研发转化中心 | 2026-05-21 | — | — | WO | claimed |
| US-20260137650-A1 | MODULATORS OF RAR RELATED ORPHAN RECEPTORS (RORs) | 11949098 CANADA INC (CA) | 2026-05-21 | — | — | US | claimed |
| WO-2026105121-A1 | ANTICANCER FORMULATIONS AND USES THEREOF | INTRAGEL THERAPEUTICS LTD. (IL) | 2026-05-21 | — | — | WO | claimed |
| WO-1983000486-A1 | METHOD FOR THE DIAGNOSTIC AND THE THERAPEUTIC TREATMENT OF TUMORS AND/OR INFECTIOUS DISEASES OF ALL SORTS BY THE USE OF ALKALOID COMPOSITIONS OR THE SALTS THEREOF | NOWICKY, WASSYL | 1983-02-17 | — | — | WO | claimed |
| EP-0055870-A1 | Pyridylmethyl esters of selected bio-affecting carboxylic acids, process for preparing and pharmaceutical composition comprising the same | MERCK & CO. INC. (US) | 1982-07-14 | — | — | EP | claimed |
| US-4332797-A | ANTITUMOR AGENTS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-06-01 | — | — | US | claimed |
| EP-0051278-A1 | Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1982-05-12 | — | — | EP | claimed |
| US-4275000-A | Peptide macromolecular complexes | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1981-06-23 | — | — | US | claimed |
| US-4261910-A | COUPLING WITH ESTRADIOL THROUGH DIFUNCTIONAL COMPOUND | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1981-04-14 | — | — | US | claimed |
| US-4218471-A | Process for the treatment of humans suffering from undesired urotoxic side effects caused by cytostatically active alkylating agents | ASTA-WERKE AKTIENGESELLSCHAFT CHEMISCHE FABRIK (DE) | 1980-08-19 | — | — | US | claimed |
| EP-0010964-A1 | Ravidomycin, process of preparation and pharmaceutical compositions containing same | AYERST, MCKENNA AND HARRISON INC. (CA) | 1980-05-14 | — | — | EP | claimed |
| US-4147767-A | CROSSLINKED WITH FORMALDEHYDE OR GLUTARALDEHYDE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1979-04-03 | — | — | US | claimed |
| EP-0000938-A1 | Macromolecular covalent conjugates, methods for preparing and pharmaceutical compositions containing them | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1979-03-07 | — | — | EP | claimed |