Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 14/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319525 | 0.89 | HDAC2 (0.67) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4292404 | 0.86 | HDAC2 (0.83) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6418581 | 0.83 | HDAC3 (0.56) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4910382 | 0.81 | HDAC2 (0.77) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4311936 | 0.81 | HDAC3 (0.73) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5481964 | 0.80 | HDAC3 (0.55) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5319421 | 0.79 | HDAC3 (0.80) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4022511 | 0.76 | HDAC1 (1.00) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4186587 | 0.76 | HDAC3 (0.49) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4326733 | 0.76 | HDAC3 (0.49) | HDAC2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009089598-A2 | MSMB-GENE METHYLATION BASED DIAGNOSIS, STAGING AND PROGNOSIS OF PROSTATE CANCER | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2009-07-23 | — | — | WO | disclosed |