Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLN | Q9BYT8 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL29012901 | 0.83 | CYP3A4 (0.55) | NLNCYP3A4SLC7A5 | |
| SCHEMBL28194192 | 0.80 | NLN (0.40) | NLN | |
| SCHEMBL6114085 | 0.78 | CYP3A4 (0.62) | NLNCYP3A4SLC7A5 | |
| SCHEMBL28114917 | 0.77 | FFAR1 (0.42) | — | |
| SCHEMBL15670833 | 0.76 | CYP3A4 (0.53) | NLNCYP3A4SLC7A5 | |
| SCHEMBL28913772 | 0.75 | CYP3A4 (0.49) | NLNCYP3A4SLC7A5 | |
| SCHEMBL27189120 | 0.75 | CYP3A4 (0.55) | NLNCYP3A4SLC7A5 | |
| SCHEMBL388562 | 0.74 | CYP3A4 (0.73) | CYP3A4SLC7A5 | |
| Sulfuric Acid SCHEMBL11052847 | 0.74 | CYP3A4 (0.57) | NLNCYP3A4SLC7A5 | |
| SCHEMBL10847030 | 0.74 | CYP3A4 (0.53) | CYP3A4SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2945647-A2 | IMMUNOGENIC WT-1 PEPTIDES AND METHODS OF USE THEREOF | Memorial Sloan Kettering Cancer Center (US) | 2015-11-25 | — | — | EP | disclosed |
| WO-2014113490-A2 | IMMUNOGENIC WT-1 PEPTIDES AND METHODS OF USE THEREOF | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2014-07-24 | — | — | WO | disclosed |
| WO-2009132660-A1 | AGENTS BINDING TO MEGALIN OR SEX HORMONE BINDING GLOBULIN AND COMPOSITIONS THEROF FOR TREATMENT OF STEROID DEPENDENT CANCERS | RECEPTICON APS (DK) | 2009-11-05 | — | — | WO | disclosed |
| EP-1499888-A4 | CONFORMATIONALLY CONSTRAINED PEPTIDES THAT BIND THE ORL-1 RECEPTOR | EURO CELTIQUE SA (LU) | 2005-10-19 | — | — | EP | disclosed |
| WO-2005037854-A2 | IMMUNOGENIC PEPTIDES | GENZYME CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |
| EP-1499888-A2 | CONFORMATIONALLY CONSTRAINED PEPTIDES THAT BIND THE ORL-1 RECEPTOR | Euro-Celtique S.A. (LU) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003093294-A2 | CONFORMATIONALLY CONSTRAINED PEPTIDES THAT BIND THE ORL-1 RECEPTOR | EURO-CELTIQUE S.A. (LU) | 2003-11-13 | — | — | WO | disclosed |