SCHEMBL4309937

SCHEMBL4309937

CC(NC(=O)c1cc(Cl)ccc1OCCc1c(F)cccc1F)c1ccc(C(=O)O)cc1

nearest known ligand 0.65

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 20/20 0.65
PTGER2 P43116 5/20 0.65
PTGDR Q13258 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692096 1.00 PTGER4 (0.65) PTGER4PTGER2PTGDR
SCHEMBL4014379 0.92 PTGER4 (0.54) PTGER4PTGER2
SCHEMBL691790 0.90 PTGER4 (0.66) PTGER4PTGER2PTGDR
SCHEMBL692571 0.87 PTGER4 (0.72) PTGER4PTGER2PTGDR
SCHEMBL4014374 0.85 PTGER4 (0.79) PTGER4PTGER2
SCHEMBL4018036 0.84 PTGER4 (0.63) PTGER4PTGER2PTGDR
SCHEMBL692263 0.84 PTGER4 (0.71) PTGER4PTGER2PTGDR
SCHEMBL691803 0.84 PTGER4 (0.75) PTGER4PTGER2PTGDR
SCHEMBL30114935 0.84 PTGER4 (0.75) PTGER4PTGER2PTGDR
SCHEMBL6496168 0.84 PTGER4 (0.75) PTGER4PTGER2PTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1756043-B1 ORTHO SUBSTITUTED ARYL OR HETEROARYL AMIDE COMPOUNDS RAQUALIA PHARMA INC (JP) 2009-07-01 EP disclosed