Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR1E | P28566 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3622589 | 0.99 | MEN1 (0.49) | KMT2AMEN1L3MBTL1GAALMNA | |
| SCHEMBL3620352 | 0.85 | MAPT (0.66) | KMT2AMEN1L3MBTL1GAALMNA | |
| SCHEMBL3622984 | 0.84 | GAA (0.50) | KMT2AMEN1L3MBTL1GAAMAPT | |
| Hydrochloric Acid SCHEMBL6047567 | 0.83 | GAA (0.49) | KMT2AMEN1L3MBTL1GAAMAPT | |
| SCHEMBL3619643 | 0.76 | SMN1; SMN2 (0.64) | KMT2AMEN1L3MBTL1GAALMNA | |
| Hydrochloric Acid SCHEMBL3622508 | 0.76 | MEN1 (0.51) | KMT2AMEN1L3MBTL1GAALMNA | |
| Hydrochloric Acid SCHEMBL3616820 | 0.75 | SMN1; SMN2 (0.63) | KMT2AMEN1L3MBTL1GAALMNA | |
| SCHEMBL3616972 | 0.75 | MEN1 (0.57) | KMT2AMEN1L3MBTL1GAALMNA | |
| Hydrochloric Acid SCHEMBL3624280 | 0.74 | MEN1 (0.57) | KMT2AMEN1L3MBTL1GAALMNA | |
| Hydrochloric Acid SCHEMBL3619589 | 0.74 | MEN1 (0.56) | KMT2AMEN1L3MBTL1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566715-B2 | Substituted sulfonamide compounds useful for the prophylaxis and treatment of conditions relating to obesity, type II diabetes and/or disorders of the central nervous system | BIOVITRUM AB (SE) | 2009-07-28 | — | — | US | claimed |