Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 3/20 | 0.38 |
| ▸ | EDNRA | P25101 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 6/20 | 0.36 |
| ▸ | ACACA | Q13085 | 6/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | MST1R | Q04912 | 1/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431036 | 0.95 | ACACB (0.35) | EDNRBEDNRAACACBACACAGSK3B | |
| SCHEMBL432196 | 0.89 | S1PR1 (0.34) | EDNRBEDNRAACACBACACA | |
| SCHEMBL431302 | 0.89 | EDNRB (0.42) | EDNRBEDNRA | |
| SCHEMBL432195 | 0.88 | EDNRB (0.34) | EDNRBEDNRAACACBACACAGSK3B | |
| SCHEMBL430208 | 0.88 | EDNRB (0.34) | EDNRBEDNRAHSD17B1HDAC1HDAC2 | |
| SCHEMBL430167 | 0.88 | ABL1 (0.37) | EDNRBEDNRAACACBACACA | |
| SCHEMBL430119 | 0.87 | KLKB1 (0.34) | EDNRBEDNRA | |
| SCHEMBL431058 | 0.86 | ACACB (0.40) | ACACBACACA | |
| SCHEMBL432538 | 0.86 | ACACB (0.31) | ACACBACACA | |
| SCHEMBL13065648 | 0.86 | ACACB (0.34) | EDNRBEDNRAACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065066-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| WO-2010133232-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065066-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | EDNRB 4122/4885EDNRA 4159/4885ACACB 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.