SCHEMBL4313032

SCHEMBL4313032

CCN(CC)c1ccc2cc(-c3cc[n+](CCO)cc3)c(=O)oc2c1.Cc1ccc(O)cc1S(=O)(=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.49
MEN1 O00255 9/20 0.46
KMT2A Q03164 9/20 0.46
L3MBTL1 Q9Y468 4/20 0.46
MAPK1 P28482 3/20 0.46
PKM P14618 2/20 0.46
MAPT P10636 10/20 0.44
LMNA P02545 5/20 0.44
SMN1; SMN2 Q16637 6/20 0.43
KDM4E B2RXH2 6/20 0.43
ATM Q13315 5/20 0.43
TDP1 Q9NUW8 3/20 0.43
MIF P14174 2/20 0.43
GAA P10253 2/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
ALDH1A1 P00352 6/20 0.43
HPGD P15428 4/20 0.43
HTT P42858 4/20 0.42
USP2 O75604 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4299388 0.92 MIF (0.44) MEN1KMT2AKDM4EATMTDP1
SCHEMBL4302030 0.92 CYP19A1 (0.51) CYP19A1MEN1KMT2AL3MBTL1MAPK1
SCHEMBL4302369 0.90 CYP19A1 (0.46) CYP19A1MEN1KMT2AL3MBTL1MAPK1
SCHEMBL4309620 0.90 CYP19A1 (0.46) CYP19A1MEN1KMT2AL3MBTL1MAPK1
Sulfuric Acid SCHEMBL4302159 0.87 CYP19A1 (0.60) CYP19A1MEN1KMT2AL3MBTL1MAPK1
SCHEMBL4313028 0.85 MEN1 (0.56) CYP19A1MEN1KMT2AL3MBTL1MAPK1
SCHEMBL4302206 0.85 CYP19A1 (0.68) CYP19A1MEN1KMT2AL3MBTL1MAPK1
Bromide SCHEMBL4313103 0.84 CYP19A1 (0.67) CYP19A1MEN1KMT2AL3MBTL1MAPK1
SCHEMBL4301921 0.82 MIF (0.42) MEN1KMT2AKDM4EATMTDP1
SCHEMBL4299901 0.82 MIF (0.47) MEN1KMT2AKDM4EATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009124800-A1 CATIONIC DIRECT DYES AND AGENTS FOR DYEING FIBERS CONTAINING KERATIN HENKEL AG & CO. KGAA (DE) 2009-10-15 WO disclosed