⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177320 | 0.64 | — | — | |
| SCHEMBL8356300 | 0.60 | — | — | |
| SCHEMBL1044296 | 0.59 | CYP3A4 (0.34) | — | |
| SCHEMBL6156017 | 0.59 | — | — | |
| SCHEMBL2119425 | 0.57 | FFAR3 (0.40) | — | |
| SCHEMBL1982906 | 0.57 | — | — | |
| Cyclohexane SCHEMBL1079006 | 0.57 | FFAR3 (0.41) | — | |
| SCHEMBL21950922 | 0.53 | FFAR3 (0.36) | — | |
| SCHEMBL21950919 | 0.53 | FFAR3 (0.36) | — | |
| SCHEMBL3097649 | 0.53 | FFAR3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605272-B2 | IGF-1R inhibitor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20090054508-A1 | IGF-1R INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1847532-A1 | IGF-1R INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |