Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170404 | 1.00 | BACE1 (1.00) | BACE1 | |
| SCHEMBL1170454 | 0.93 | BACE1 (0.87) | BACE1 | |
| SCHEMBL1170707 | 0.91 | BACE1 (1.00) | BACE1 | |
| SCHEMBL1171223 | 0.91 | BACE1 (1.00) | BACE1 | |
| SCHEMBL1170517 | 0.89 | BACE1 (0.81) | BACE1 | |
| SCHEMBL1170679 | 0.89 | BACE1 (0.87) | BACE1 | |
| SCHEMBL4315190 | 0.88 | BACE1 (1.00) | BACE1 | |
| SCHEMBL1170280 | 0.88 | BACE1 (1.00) | BACE1 | |
| SCHEMBL1430105 | 0.88 | BACE1 (1.00) | BACE1 | |
| SCHEMBL1170383 | 0.88 | BACE1 (1.00) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136350-A1 | NOVEL CLASS OF SPIRO PIPERIDINES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | PFIZER INC. (US) | 2009-11-12 | — | — | WO | disclosed |