⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659962 | 0.70 | — | — | |
| SCHEMBL28285613 | 0.70 | — | — | |
| SCHEMBL27320806 | 0.70 | — | — | |
| SCHEMBL27441941 | 0.70 | — | — | |
| SCHEMBL27504389 | 0.70 | — | — | |
| SCHEMBL27553084 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL27624140 | 0.69 | — | — | |
| SCHEMBL8097509 | 0.65 | — | — | |
| SCHEMBL7659827 | 0.65 | — | — | |
| SCHEMBL34471497 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111433197-A | Solid forms of plasma kallikrein inhibitors and salts thereof | 卡尔维斯塔制药有限公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-110325513-A | The method for preparing substituted biphenyl | 巴斯夫欧洲公司 | 2019-10-11 | — | — | CN | disclosed |
| WO-2014100233-A1 | IRON CHELATORS AND USE THEREOF FOR REDUCING TRANSPLANT FAILURE DURING REJECTION EPISODES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014036414-A2 | IRON CHELATORS AND USE THEREOF FOR REDUCING TRANSPLANT FAILURE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-03-06 | — | — | WO | disclosed |
| EP-2043636-A2 | (COMBI) COMPOSITIONS FOR THE TREATMENT OF MUCORMYCOSIS COMPRISING IRON CHELATOR AND ANTIFUNGAL AGENT | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008008537-A2 | COMBI) COMPOSITIONS FOR THE TREATMENT OF MUCORMYCOSIS. COMPRISING IRON CHELATOR AND ANTIFUNGAL AGENT | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2008-01-17 | — | — | WO | disclosed |