SCHEMBL4315748

SCHEMBL4315748

CCCC1=C(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)CN(c2ccc(O[C@H]3CC[C@H](O)CC3)cc2)C(CC)=N1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC33A1 O00400 19/20 0.52
PPARG P37231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4018344 0.88 SLC33A1 (0.49) SLC33A1PPARG
SCHEMBL4008048 0.86 SLC33A1 (0.47) SLC33A1PPARG
SCHEMBL4009750 0.86 SLC33A1 (0.44) SLC33A1
SCHEMBL12349029 0.79 SLC33A1 (0.57) SLC33A1PPARG
SCHEMBL1887943 0.79 SLC33A1 (0.57) SLC33A1PPARG
SCHEMBL1887940 0.79 SLC33A1 (0.57) SLC33A1PPARG
SCHEMBL1897145 0.79 SLC33A1 (0.57) SLC33A1PPARG
SCHEMBL1888183 0.78 SLC33A1 (0.56) SLC33A1PPARG
SCHEMBL2879614 0.78 SLC33A1 (0.56) SLC33A1PPARG
SCHEMBL2838606 0.78 SLC33A1 (0.56) SLC33A1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009133970-A1 CRYSTALLINE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-11-05 WO disclosed