SCHEMBL43159

SCHEMBL43159

CC(C)(C)OC(=O)N1CC(C(=O)O)C1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.53
HPGD P15428 1/20 0.51
HSD17B10 Q99714 1/20 0.48
USP2 O75604 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
RECQL P46063 1/20 0.45
EPHX1 P07099 1/20 0.45
RORC P51449 1/20 0.43
GPR119 Q8TDV5 1/20 0.42
POLB P06746 1/20 0.42
PTPN2 P17706 1/20 0.41
PTPN1 P18031 1/20 0.41
PTPN6 P29350 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18275033 0.92 HPGD (0.53) NR1H2HPGDHSD17B10USP2SMN1; SMN2
SCHEMBL20220628 0.92 NR1H2 (0.54) NR1H2HPGDHSD17B10USP2SMN1; SMN2
SCHEMBL57263 0.92 NR1H2 (0.54) NR1H2HPGDHSD17B10USP2SMN1; SMN2
SCHEMBL89062 0.92 NR1H2 (0.54) NR1H2HPGDHSD17B10USP2SMN1; SMN2
SCHEMBL8649028 0.90 NR1H2 (0.45) NR1H2HPGDHSD17B10USP2SMN1; SMN2
Hexane SCHEMBL28403969 0.90 NR1H2 (0.49) NR1H2HPGDHSD17B10USP2SMN1; SMN2
SCHEMBL27152584 0.87 NR1H2 (0.43) NR1H2HPGDHSD17B10USP2SMN1; SMN2
SCHEMBL25271451 0.86 NR1H2 (0.49) NR1H2HPGDHSD17B10USP2SMN1; SMN2
SCHEMBL7866668 0.86 NR1H2 (0.49) NR1H2HPGDHSD17B10USP2SMN1; SMN2
SCHEMBL14478714 0.86 NR1H2 (0.49) NR1H2HPGDHSD17B10USP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2244 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146046-A1 BICYCLIC FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2026-05-28 US disclosed
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors MISSION THERAPEUTICS LIMITED (GB) 2026-05-26 US disclosed
US-12637458-B2 Imidazo[1,2-a]pyridine compounds and their use in therapy IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2026-05-26 US disclosed
CN-122080121-A Linker and use thereof in ligand drug conjugates 2026-05-26 CN disclosed
CN-122079847-A Key intermediate of 3-hydroxymethyl azetidine-1-carboxylic acid tert-butyl ester and preparation method thereof 2026-05-26 CN disclosed
US-20260138977-A1 MODULATORS OF BETA CATENIN AND USES THEREOF DEWPOINT THERAPEUTICS INC (US) 2026-05-21 US disclosed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP disclosed
US-12630548-B2 Azetidine derivatives for the treatment of integrin associated diseases THE UNIVERSITY OF NOTTINGHAM (GB) 2026-05-19 US disclosed
US-20260132109-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2026-05-14 US disclosed
EP-3829559-B1 INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION MERCK SHARP & DOHME LLC (US) 2026-05-13 EP disclosed
US-6239151-B1 TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES, OSTEOARTHRITIS, RESPIRATORY DISEASES, TUMORS, CACHEXIA, CARDIOVASCULAR DISEASES, FEVER, HAEMORRHAGE AND SEPSIS, HYDRAZINE DERIVATIVES, HOFFMANN-LA ROCHE INC. 2001-05-29 US disclosed
WO-2000071518-A2 HETEROCYCLIC ANALGESIC COMPOUNDS AND THEIR USE SEPRACOR, INC. (US) 2000-11-30 WO disclosed
WO-2000066557-A1 NEW COMPOUNDS ASTRAZENECA AB (SE) 2000-11-09 WO disclosed
US-6127391-A A PEPTIDE MIMETIC COMPOUND FOR STIMULATING THE RELEASE OF GROWTH HORMONE FROM THE PITUITARY NOVO NORDISK A/S (DK) 2000-10-03 US disclosed
WO-2000038680-A1 AZABICYCLOALKANES AS CCR5 MODULATORS PFIZER LIMITED (GB) 2000-07-06 WO disclosed
US-6020368-A MICROBIOCIDES HINKS JEREMY DAVID (US) 2000-02-01 US disclosed
US-5977178-A Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 1999-11-02 US disclosed
EP-0869974-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1998-10-14 EP disclosed
WO-1997023508-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-07-03 WO disclosed
WO-1992002521-A1 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-02-20 WO disclosed