Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.57 |
| ▸ | DAO | P14920 | 3/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL649557 | 0.91 | PTPN1 (0.64) | PTPN1DAOPTPN2 | |
| SCHEMBL3216277 | 0.88 | PTPN1 (0.49) | PTPN1DAOPTPN2 | |
| SCHEMBL3223283 | 0.88 | PTPN1 (0.49) | PTPN1DAOPTPN2 | |
| SCHEMBL3221771 | 0.87 | PTPN1 (0.52) | PTPN1DAOPTPN2NR1H3NR1H2 | |
| SCHEMBL3215930 | 0.86 | PTPN1 (0.56) | PTPN1DAOPTPN2NR1H3NR1H2 | |
| SCHEMBL3214274 | 0.85 | PTPN1 (0.52) | PTPN1DAOPTPN2GPR84 | |
| SCHEMBL3214264 | 0.85 | PTPN1 (0.53) | PTPN1DAOPTPN2NR1H3NR1H2 | |
| SCHEMBL3216871 | 0.84 | PTPN1 (0.50) | PTPN1PTPN2NR1H3NR1H2 | |
| SCHEMBL3226681 | 0.84 | PTPN1 (0.63) | PTPN1PTPN2 | |
| SCHEMBL3213356 | 0.83 | PTPN1 (0.58) | PTPN1DAOPTPN2NR1H3GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181928-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-07-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181928-A1 | ORGANIC COMPOUNDS | PTPRS, PTPRO, PTPRC | PTPN1 21/4885DAO 2562/4885PTPN2 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.