Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450564 | 0.81 | PREP (0.47) | HRH3KCNH2 | |
| SCHEMBL4321123 | 0.80 | HRH3 (0.42) | HRH3KCNH2 | |
| SCHEMBL1507253 | 0.77 | HRH3 (0.52) | HRH3 | |
| SCHEMBL4314824 | 0.76 | HRH3 (0.48) | HRH3KCNH2 | |
| SCHEMBL4323402 | 0.76 | HRH3 (0.48) | HRH3KCNH2 | |
| SCHEMBL4329752 | 0.76 | HRH3 (0.48) | HRH3KCNH2 | |
| SCHEMBL4326925 | 0.75 | HRH3 (0.59) | HRH3KCNH2 | |
| SCHEMBL4324925 | 0.73 | HRH3 (0.62) | HRH3KCNH2 | |
| SCHEMBL4321163 | 0.73 | HRH3 (0.45) | HRH3KCNH2 | |
| SCHEMBL4315553 | 0.72 | HRH3 (0.61) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143153-A1 | SUBSTITUTED PYRROLIDINE AMIDES AS MODULATORS OF THE HISTAMINE H3 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-26 | — | — | WO | claimed |
| WO-2009143153-A1 | SUBSTITUTED PYRROLIDINE AMIDES AS MODULATORS OF THE HISTAMINE H3 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-26 | — | — | WO | disclosed |