SCHEMBL431806

SCHEMBL431806

CCOP(=O)(CCl)OCC

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.60
TP53 P04637 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
PPARD Q03181 2/20 0.50
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
ACHE P22303 1/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11308525 0.82 TSHR (0.43) TSHRTP53TDP1PPARD
SCHEMBL28008094 0.78 MEN1 (0.39) TSHRTP53TDP1PPARDMEN1
SCHEMBL524900 0.78 PPARD (0.58) TSHRTP53TDP1PPARDALDH1A1
SCHEMBL5664469 0.78 TSHR (0.48) TSHRTP53TDP1PPARDMEN1
SCHEMBL10481895 0.76 TSHR (0.75) TSHRTP53TDP1PPARDMEN1
SCHEMBL4060148 0.76 TSHR (0.52) TSHRTP53TDP1PPARDMEN1
SCHEMBL3313657 0.75 PPARD (0.70) TSHRTP53TDP1PPARDMEN1
SCHEMBL5961215 0.75 TSHR (1.00) TSHRTP53TDP1PPARDMEN1
SCHEMBL282472 0.75 TSHR (0.67) TSHRTP53TDP1PPARDMEN1
SCHEMBL26483 0.75 TSHR (1.00) TSHRTP53TDP1PPARDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118813195-A Environment-friendly weather-resistant flame-retardant adhesive and preparation method and application thereof 李水永 2024-10-22 CN claimed
CN-118507986-A High-thermal-stability battery diaphragm and preparation method thereof 湖南博盛新能源技术有限公司 2024-08-16 CN claimed
CN-118271578-A Polymer with phosphonic acid structure in side chain, synthesis method and application thereof in high-temperature proton exchange membrane fuel cell 中国科学院山西煤炭化学研究所 2024-07-02 CN claimed
CN-116922881-A Thermal insulation composite board and preparation method thereof 安徽宏志建材科技有限公司 2023-10-24 CN claimed
CN-111187325-A Anti-tumor (4' R) -methyl- α -L-ribofuranose nucleoside and preparation method thereof 郑州大学 2020-05-22 CN claimed
CN-103664960-B Pu Na is for the preparation method of Buddhist nun SUZHOU MINGYUE MEDICAL TECHNOLOGY CO., LTD. (CN) 2015-08-05 CN claimed
CN-103664960-A Preparation method for Ponatinib SUZHOU MIRACPHARMA TECHNOLOGY CO LTD 2014-03-26 CN claimed
EP-3801553-B1 PRODRUGS OF FULVESTRANT KASHIV BIOSCIENCES LLC (US) 2026-03-25 EP disclosed
US-20250298333-A1 POLYESTER RESIN COMPOSITION, ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, DEVELOPER, AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2025-09-25 US disclosed
US-20250281519-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETO EMORY UNIVERSITY 2025-09-11 US disclosed
CN-119751939-A Waterproof PET film for photovoltaic backboard and preparation method thereof 浙江大东南股份有限公司 2025-04-04 CN disclosed
CN-118813195-A Environment-friendly weather-resistant flame-retardant adhesive and preparation method and application thereof 李水永 2024-10-22 CN disclosed
CN-118507986-B High-thermal-stability battery diaphragm and preparation method thereof 湖南博盛新能源技术有限公司 2024-09-24 CN disclosed
EP-0224209-A2 Process for recovery of rare metals SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-06-03 EP disclosed
EP-0204217-A1 Recovery of metals adsorbed on chelating agents SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-12-10 EP disclosed
EP-0190676-A1 Cis-1,3,5-triamino 2,4,6-cyclohexanetriol derivatives, their use, process for their preparation and pharmaceutical preparations containing them Laboratorien Hausmann AG (CH) 1986-08-13 EP disclosed
US-4565673-A USING A HALOGEN-FREE ACID FOLLOWED BY A HALOGEN-CONTAINING SOLUTION FOR SELECTIVE SEPARATION FROM OTHER METALS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-01-21 US disclosed
EP-0148158-A2 Process for eluting indium from a chelate resin containing adsorbed indium SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-07-10 EP disclosed
US-4141734-A SUBSTITUTED ORGANIC DI- OR TRISULFIDE ANTIDEPOSIT AGENTS CIBA-GEIBY AG (CH) 1979-02-27 US disclosed
US-4092108-A AMINE SUBSTITUTED PHOSPHONIC ACID DERIVATIVES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1978-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250281519-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETO NTPCR, TYMP, MTAP TSHR 3042/4885TP53 602/4885TDP1 369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.