SCHEMBL4319262

SCHEMBL4319262

Cc1ccc(NS(=O)(=O)C2CCCCC2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
MAPT P10636 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
LMNA P02545 1/20 0.55
TP53 P04637 1/20 0.55
ATM Q13315 1/20 0.55
FKBP1A P62942 1/20 0.51
BRPF1 P55201 1/20 0.51
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
BRD4 O60885 4/20 0.48
SGK1 O00141 1/20 0.48
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
MAP2K4 P45985 1/20 0.46
MEN1 O00255 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL257524 0.91 CA1 (0.53) ALDH1A1MAPTSMN1; SMN2LMNATP53
SCHEMBL10650094 0.81 BRD4 (0.52) MAPTTP53BRPF1CA1CA2
SCHEMBL27396497 0.81 EPHX1 (0.49) ALDH1A1MAPTSMN1; SMN2LMNATP53
SCHEMBL25647120 0.80 SGK1 (0.47) ALDH1A1MAPTSMN1; SMN2LMNATP53
SCHEMBL14582136 0.80 SMN1; SMN2 (0.59) ALDH1A1MAPTSMN1; SMN2LMNATP53
SCHEMBL21590230 0.80 CA1 (0.50) FKBP1ABRPF1CA1CA2BRD4
SCHEMBL17404466 0.79 BRD4 (0.51) ALDH1A1BRPF1CA1CA2BRD4
SCHEMBL20946432 0.78 SGK1 (0.48) ALDH1A1MAPTSMN1; SMN2LMNABRPF1
SCHEMBL8264979 0.78 KMT2A (0.48) BRPF1CA1CA2BRD4SGK1
SCHEMBL1267272 0.76 SGK1 (0.43) BRPF1BRD4SGK1MAP2K4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035890-A9 AT LOW TEMPERATURE, FAST HARDENING COMPOSITION FOR PREPARING PROTECTING FILM, PROTECTING FILM PREPARED THEREFROM, AND SUBSTRATE COMPRISING THE SAME LG CHEMICAL LTD (KR) 2009-04-23 WO disclosed
WO-2008035890-A1 AT LOW TEMPERATURE, FAST HARDENING COMPOSITION FOR PREPARING PROTECTING FILM, PROTECTING FILM PREPARED THEREFROM, AND SUBSTRATE COMPRISING THE SAME LG CHEM, LTD. (KR) 2008-03-27 WO disclosed