Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.69 |
| ▸ | TTR | P02766 | 6/20 | 0.69 |
| ▸ | EYA3 | Q99504 | 4/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | PGR | P06401 | 2/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.64 |
| ▸ | EYA2 | O00167 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26810424 | 0.91 | SLC22A12 (0.67) | SLC22A12TTREYA3CYP2C19PTPN1 | |
| SCHEMBL26810887 | 0.89 | SLC22A12 (0.65) | SLC22A12TTREYA3CYP2C19PTPN1 | |
| SCHEMBL4311788 | 0.88 | SLC22A12 (0.73) | SLC22A12TTREYA3CYP2C19PTPN1 | |
| SCHEMBL26668816 | 0.88 | SLC22A12 (0.53) | SLC22A12TTREYA3CYP2C19PTPN1 | |
| SCHEMBL26811390 | 0.84 | PTPN1 (0.68) | SLC22A12TTREYA3CYP2C19PTPN1 | |
| SCHEMBL26811502 | 0.82 | PTPN1 (0.66) | SLC22A12TTREYA3CYP2C19PTPN1 | |
| SCHEMBL1288090 | 0.82 | SLC22A12 (1.00) | SLC22A12TTREYA3CYP2C19PTPN1 | |
| SCHEMBL30357404 | 0.82 | SLC22A12 (0.81) | SLC22A12TTREYA3CYP2C19PTPN1 | |
| SCHEMBL30258768 | 0.81 | SLC22A12 (0.80) | SLC22A12TTREYA3CYP2C19PTPN1 | |
| SCHEMBL15698041 | 0.81 | SLC22A12 (0.80) | SLC22A12TTREYA3CYP2C19PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023058975-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING HSP47 INCLUDING BENZOFURANYL HYDROXYPHENYL METHANONE DERIVATIVE | (주)이노보테라퓨틱스 | 2023-04-13 | — | — | WO | claimed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2023058975-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING HSP47 INCLUDING BENZOFURANYL HYDROXYPHENYL METHANONE DERIVATIVE | (주)이노보테라퓨틱스 | 2023-04-13 | — | — | WO | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200278346-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ADJACENT ACQUISITION CO., LLC | 2020-09-03 | — | — | US | disclosed |
| EP-3681504-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | Icagen, Inc. (US) | 2020-07-22 | — | — | EP | disclosed |
| WO-2019055754-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN, INC. (US) | 2019-03-21 | — | — | WO | disclosed |
| US-20150309021-A1 | Advanced Drug Development and Manufacturing | LOS ALAMOS NATIONAL SECURITY, LLC | 2015-10-29 | — | — | US | disclosed |
| EP-2511844-B1 | X-ray microscope | XRPRO SCIENCES INC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2511844-A2 | Advanced drug development and manufacturing | Los Alamos National Security, LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| EP-2084519-B1 | X-RAY FLUORESCENCE ANALYSIS METHOD | LOS ALAMOS NAT SECURITY LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2084519-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | Los Alamos National Security, LLC (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008127291-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-10-23 | — | — | WO | disclosed |
| US-20080220441-A1 | Advanced drug development and manufacturing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-11 | — | — | US | disclosed |