SCHEMBL4320439

SCHEMBL4320439

CC(C)(C)OOOOC(=O)c1ccccc1OOC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.44
ALDH1A1 P00352 3/20 0.44
TSHR P16473 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ELANE P08246 2/20 0.38
SLC6A3 Q01959 2/20 0.36
KDM4E B2RXH2 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
LMNA P02545 1/20 0.36
SLC6A4 P31645 1/20 0.36
HPGD P15428 3/20 0.35
XBP1 P17861 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
ESR1 P03372 2/20 0.33
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33
HMGB1 P09429 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1469285 0.95 HSD17B10 (0.45) HSD17B10ALDH1A1TSHRTDP1MAPT
SCHEMBL28518702 0.90 HSD17B10 (0.49) HSD17B10ALDH1A1TSHRTDP1MAPT
SCHEMBL2507510 0.83 HSD17B10 (0.44) HSD17B10ALDH1A1TSHRTDP1MAPT
SCHEMBL11424877 0.83 MAPT (0.52) HSD17B10ALDH1A1TSHRTDP1MAPT
SCHEMBL28410221 0.82 HSD17B10 (0.40) HSD17B10ALDH1A1TSHRTDP1MAPT
SCHEMBL29390328 0.81 TSHR (0.53) HSD17B10ALDH1A1TSHRTDP1ELANE
SCHEMBL629428 0.81 TSHR (0.53) HSD17B10ALDH1A1TSHRTDP1ELANE
SCHEMBL31571285 0.80 ELANE (0.58) HSD17B10ALDH1A1TSHRTDP1MAPT
SCHEMBL29288745 0.79 HSD17B10 (0.53) HSD17B10ALDH1A1TSHRTDP1MAPT
SCHEMBL29022920 0.79 HSD17B10 (0.41) HSD17B10ALDH1A1TSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10144820-B2 Crosslinked rubber, member for tires, vibration-proofing member, member for belts, and rubber composition JSR CORPORATION (JP) 2018-12-04 US disclosed
EP-3064545-B1 MEMBER FOR TIRES, VIBRATION-PROOFING MEMBER AND MEMBER FOR BELTS JSR CORP (JP) 2018-06-20 EP disclosed
US-20170233561-A1 CROSSLINKED RUBBER, MEMBER FOR TIRES, VIBRATION-PROOFING MEMBER, MEMBER FOR BELTS, AND RUBBER COMPOSITION JSR CORPORATION (JP) 2017-08-17 US disclosed
US-9683095-B2 Crosslinked rubber, member for tires, vibration-proofing member, member for belts, and rubber composition JSR CORPORATION (JP) 2017-06-20 US disclosed
EP-3064545-A1 CROSSLINKED RUBBER, MEMBER FOR TIRES, VIBRATION-PROOFING MEMBER, MEMBER FOR BELTS, AND RUBBER COMPOSITION JSR Corporation (JP) 2016-09-07 EP disclosed
US-20160215127-A1 CROSSLINKED RUBBER, MEMBER FOR TIRES, VIBRATION-PROOFING MEMBER, MEMBER FOR BELTS, AND RUBBER COMPOSITION JSR CORPORATION (JP) 2016-07-28 US disclosed
EP-1958980-B1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR CORP (JP) 2012-10-31 EP disclosed
EP-2135895-A1 Thermoplastic elastomer composition and method for producing the same JSR Corporation (JP) 2009-12-23 EP disclosed
EP-2130861-A2 Thermoplastic elastomer composition and method for producing the same JSR Corporation (JP) 2009-12-09 EP disclosed
US-20090270525-A1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR CORPORATION (JP) 2009-10-29 US disclosed
EP-1683832-A1 THERMOPLASTIC ELASTOMER COMPOSITION AND MOLDING THEREOF JSR Corporation (JP) 2006-07-26 EP disclosed
US-20050038186-A1 Thermoplastic elastomer composition and process for producing the same JSR CORP. (JP) 2005-02-17 US disclosed
EP-1195404-B1 THERMOPLASTIC ELASTOMER COMPOSITION JSR CORP (JP) 2004-09-29 EP disclosed
EP-1441005-A1 THERMOPLASTIC ELASTOMER COMPOSITION AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2004-07-28 EP disclosed
US-6696516-B2 A CROSSLINKED POLYMER COMPRISES AN ETHYLENE AND ALPHA OLEFINIC COPOLYMERIC RUBBER, AN ALPHA OLEFINIC POLYCRYSTALLINE; VULCANIZED RUBBER-LIKE FLEXIBILITY, LOW HARDNESS AND LOW COMPRESSION; INJECTION MOLDING JSR CORPORATION (JP) 2004-02-24 US disclosed
US-20020183441-A1 Thermoplastic elastomer composition JSR CORPORATION (JP) 2002-12-05 US disclosed
EP-1195404-A1 THERMOPLASTIC ELASTOMER COMPOSITION JSR Corporation (JP) 2002-04-10 EP disclosed
US-6077878-A FOAMED EXTRUDATE COMPRISING GRAFTED COPOLYMER OF POLYPROPYLENE RESIN AND AROMATIC VINYL MONOMER KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-06-20 US disclosed
EP-0735091-B1 Thermoplastic elastomer composition excellent in fusion bondability with an olefinic rubber, and bonded article JAPAN SYNTHETIC RUBBER CO LTD (JP) 1999-12-22 EP disclosed
EP-0735091-A2 Thermoplastic elastomer composition excellent in fusion bondability with an olefinic rubber, and bonded article JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-10-02 EP disclosed