SCHEMBL432048

SCHEMBL432048

O=C1CCCC(=O)N1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11471691 0.93 BRD4 (0.39)
SCHEMBL4011609 0.86 BRD4 (0.30)
SCHEMBL10376304 0.86
SCHEMBL58 0.86
SCHEMBL2201542 0.86
Iodide SCHEMBL31365449 0.83
SCHEMBL28948472 0.83
Fluoride SCHEMBL7176780 0.83
SCHEMBL4511932 0.83
Ammonia Solution, Strong SCHEMBL28443159 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9376397-B2 Key intermediates for the synthesis of rosuvastatin or pharmaceutically acceptable salts thereof LEK PHARMACEUTICALS D.D. (SI) 2016-06-28 US claimed
US-20150141449-A1 KEY INTERMEDIATES FOR THE SYNTHESIS OF ROSUVASTATIN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF LEK PHARMACEUTICALS D.D. (SI) 2015-05-21 US claimed
US-8338554-B2 Hyperbranched polymer and method for producing the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-12-25 US claimed
EP-2058338-B1 HYPERBRANCHED POLYMER AND METHOD FOR PRODUCING THE SAME NISSAN CHEMICAL IND LTD (JP) 2012-08-15 EP claimed
US-20120022091-A1 KEY INTERMEDIATES FOR THE SYNTHESIS OF ROSUVASTATIN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF LEK PHARMACEUTICALS D.D. (SI) 2012-01-26 US claimed
US-7868097-B2 Hybrid polymer and method for production thereof MITSUI CHEMICALS, INC. (JP) 2011-01-11 US claimed
EP-2264015-A1 Key intermediates for the synthesis of rosuvastatin or pharmaceutically acceptable salts thereof LEK Pharmaceuticals d.d. (SI) 2010-12-22 EP claimed
US-20100048845-A1 Hyperbranched polymer and method for producing the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-02-25 US claimed
US-7550622-B2 Cycloalkylamidoacid compounds, processes for making and uses thereof BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-06-23 US claimed
EP-2058338-A1 HYPERBRANCHED POLYMER AND METHOD FOR PRODUCING THE SAME Nissan Chemical Industries, Ltd. (JP) 2009-05-13 EP claimed
US-20030166622-A1 Vitamin D derivatives with acyloxy groups in the side chains, process for their production, and the use for the production of pharmaceutical agents SCHERING AG (DE) 2003-09-04 US claimed
US-20030050475-A1 Method for preparing halomethyl heterocyclic compounds BURDENIUC JUAN JESUS (US) 2003-03-13 US claimed
EP-1277742-A1 Method for preparing halomethyl heterocyclic compounds AIR PRODUCTS AND CHEMICALS, INC. (US) 2003-01-22 EP claimed
US-6492517-B1 THE PRESENT INVENTION RELATES TO A METHOD FOR PREPARING 5- AND 6-HALOMETHYL QUINOXALINES IN PRESENCE OF A RADICAL INITIATOR IN A SOLVENT SELECTED FROM THE GROUP CONSISTING OF FLUOROBENZENE, DIFLUOROBENZENES, TRIFLUOROBENZENES, AIR PRODUCTS AND CHEMICALS, INC. 2002-12-10 US claimed
US-4327191-A THEN AMINATING RHONE-POULENC INDUSTRIES (FR) 1982-04-27 US claimed
EP-0025385-A1 Preparation of anion-exchange resins by bromination of vinylaromatic polymers, and products obtained RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-03-18 EP claimed
US-4032348-A METHOD FOR FORMING PHASE HOLOGRAMS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US claimed
JP-9169673-A None JP disclosed
US-4051283-A PRINTED SHEETS CONTAINING CONCEALED IMAGES AND METHOD AND MATERIALS FOR PREPARATION AND VISUAL DEVELOPMENT OF SAME A. B. DICK COMPANY (US) 1977-09-27 US disclosed
US-4032348-A METHOD FOR FORMING PHASE HOLOGRAMS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US disclosed