SCHEMBL4321761

SCHEMBL4321761

c1ccc(-c2ccc(-c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3cc(-c5ccc(-c6ccccc6)cc5)ccc3-4)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 17/20 0.59
▸ MEN1 O00255 1/20 0.47
▸ APAF1 O14727 1/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ THRB P10828 1/20 0.47
▸ XBP1 P17861 1/20 0.47
▸ PTBP1 P26599 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ GALK1 P51570 1/20 0.47
▸ BLM P54132 1/20 0.47
▸ SMAD3 P84022 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ TDP2 O95551 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5859662 1.00 PDK2 (0.59) PDK2MEN1APAF1NPC1LMNA
SCHEMBL5859559 1.00 PDK2 (0.59) PDK2MEN1APAF1NPC1LMNA
SCHEMBL25685038 1.00 PDK2 (0.59) PDK2MEN1APAF1NPC1LMNA
SCHEMBL25584086 0.96 PDK2 (0.56) PDK2MEN1APAF1NPC1LMNA
SCHEMBL22838057 0.96 PDK2 (0.56) PDK2MEN1APAF1NPC1LMNA
SCHEMBL6294152 0.96 PDK2 (0.53) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL16912961 0.94 PDK2 (0.54) PDK2MEN1APAF1NPC1LMNA
SCHEMBL29986604 0.94 PDK2 (0.55) PDK2MEN1APAF1NPC1LMNA
SCHEMBL29512055 0.94 PDK2 (0.50) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL415665 0.94 PDK2 (0.50) PDK2MEN1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 — — US claimed
US-7175922-B2 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2007-02-13 — — US claimed
US-20060141287-A1 OLEDs with improved operational lifetime EASTMAN KODAK COMPANY 2006-06-29 — — US claimed
US-20060040131-A1 OLEDs with improved operational lifetime EASTMAN KODAK COMPANY 2006-02-23 — — US claimed
US-20050106415-A1 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2005-05-19 — — US claimed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 — — US claimed
US-7504163-B2 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY (US) 2009-03-17 — — US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 — — US disclosed
US-7175922-B2 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2007-02-13 — — US disclosed
US-20060141287-A1 OLEDs with improved operational lifetime EASTMAN KODAK COMPANY 2006-06-29 — — US disclosed
US-20060040131-A1 OLEDs with improved operational lifetime EASTMAN KODAK COMPANY 2006-02-23 — — US disclosed
US-20060008672-A1 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY 2006-01-12 — — US disclosed
US-20050106415-A1 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2005-05-19 — — US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 — — US disclosed
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