SCHEMBL4322379

SCHEMBL4322379

CC(NC(=O)C(C)NC(=O)C(N)C(C)C)C(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 3/20 0.58
MME P08473 6/20 0.56
ACE P12821 3/20 0.55
CPA1 P15085 3/20 0.55
ACE2 Q9BYF1 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051124 1.00 BACE1 (0.58) BACE1MMEACECPA1ACE2
SCHEMBL4322389 1.00 BACE1 (0.58) BACE1MMEACECPA1ACE2
Mdl-28170 SCHEMBL11370994 0.94 MME (0.61) MMEACECPA1ACE2
Mdl-28170 SCHEMBL30873029 0.94 MME (0.61) MMEACECPA1ACE2
Mdl-28170 SCHEMBL7335375 0.94 MME (0.61) MMEACECPA1ACE2
SCHEMBL29398027 0.93 BACE1 (0.62) BACE1MME
SCHEMBL30051551 0.92 MME (0.58) MMEACECPA1ACE2
SCHEMBL31005067 0.91 BACE1 (0.70) BACE1
SCHEMBL29877007 0.91 MME (0.55) BACE1MMEACECPA1ACE2
SCHEMBL31243913 0.90 BACE1 (0.67) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108290931-B Novel polypeptides having affinity for PD-L1 AFFIBODY AB (SE) 2026-05-26 CN disclosed
CN-115925917-B Anti-PVRIG protein antibodies or antibody fragments and uses thereof 合肥天港免疫药物有限公司 2026-05-19 CN disclosed
US-20250352620-A1 COMBINATION THERAPY TO TREAT BRAIN CANCER INOVIO PHARMACEUTICALS INC (US) 2025-11-20 US disclosed
CN-112261874-B Inhibition of fungal growth by manganese depletion 科·汉森有限公司 2025-06-17 CN disclosed
CN-114126646-B Sequence-based high-throughput methods to generate camelid antibodies covering a broad range of epitopes with high resolution 浙江纳米抗体技术中心有限公司 2025-05-30 CN disclosed
CN-113710807-B Microorganisms and methods for producing oxygenates from hexoses 布拉斯科公司 2025-05-30 CN disclosed
CN-112118863-B Antigenic peptides for the prevention and treatment of cancer 恩特罗姆公司 2025-05-30 CN disclosed
CN-114008197-B Metabolic engineering for simultaneous consumption of xylose and glucose to produce chemicals from second generation sugars 布拉斯科公司 2025-05-27 CN disclosed
EP-4554628-A1 HIV IMMUNOGENIC POLYPEPTIDES AND VACCINES AND USES THEREOF GILEAD SCIENCES, INC. (US) 2025-05-21 EP disclosed
CN-115074398-B Method for synthesizing dihydrochalcone by using chalcone reductase 浙江大学 2025-05-16 CN disclosed
CN-114058735-A Method for detecting hand-foot-and-mouth disease based on CRISPR technology 山东舜丰生物科技有限公司 2022-02-18 CN disclosed
CN-110386987-B Inhibitory synthetic Notch and double-target system and preparation method and application thereof 深圳市思考者医疗信息咨询有限公司 2022-02-18 CN disclosed
CN-114045277-A Base editor and construction method and application thereof 复旦大学 2022-02-15 CN disclosed
CN-107406864-B Method for producing L-serine using genetically engineered microorganisms lacking serine degradation pathway 化学生物有限公司 2022-02-11 CN disclosed
CN-110078632-B Biosynthesis method of dapoxetine intermediate and intermediate thereof 淮阴工学院 2022-02-11 CN disclosed
CN-112795625-B Method for detecting multiple nucleic acids based on CRISPR technology 山东舜丰生物科技有限公司 2022-02-08 CN disclosed
CN-114008197-A Metabolic engineering for simultaneous consumption of xylose and glucose to produce chemicals from second generation sugars 布拉斯科公司 2022-02-01 CN disclosed
CN-113993989-A Process for producing ergothioneine 丹麦科技大学 2022-01-28 CN disclosed
US-7619217-B2 High power laser induced acoustic desorption probe PURDUE RESEARCH FOUNDATION (US) 2009-11-17 US disclosed
US-20070295902-A1 High power laser induced acoustic desorption probe PURDUE RESEARCH FOUNDATION (US) 2007-12-27 US disclosed