Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742534 | 0.89 | SYK (0.62) | SYK | |
| SCHEMBL433116 | 0.88 | SYK (0.58) | SYK | |
| SCHEMBL3495163 | 0.87 | SYK (0.62) | SYK | |
| SCHEMBL3503648 | 0.87 | SYK (0.42) | SYK | |
| SCHEMBL432560 | 0.87 | SYK (0.51) | SYK | |
| SCHEMBL3494376 | 0.82 | SYK (0.63) | SYK | |
| SCHEMBL3495020 | 0.80 | SYK (0.62) | SYK | |
| SCHEMBL3495034 | 0.78 | PRKCQ (0.45) | SYK | |
| SCHEMBL429172 | 0.78 | PRKCQ (0.41) | SYK | |
| SCHEMBL763115 | 0.77 | SYK (0.79) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595982-A1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | Rigel Pharmaceuticals, Inc. (US) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012012619-A1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |