Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | GALR3 | O60755 | 1/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339874 | 0.91 | TRPV1 (0.61) | TRPV1KDM4ENPC1RAB9AGALR3 | |
| SCHEMBL5385421 | 0.88 | TRPV1 (0.76) | TRPV1KDM4ENPC1RAB9AGALR3 | |
| SCHEMBL8363015 | 0.88 | TRPV1 (0.76) | TRPV1KDM4ENPC1RAB9AGALR3 | |
| SCHEMBL13578654 | 0.87 | TRPV1 (0.70) | TRPV1KDM4ENPC1RAB9AGALR3 | |
| SCHEMBL10112878 | 0.87 | TRPV1 (0.74) | TRPV1KDM4ENPC1RAB9AGALR3 | |
| SCHEMBL10803698 | 0.87 | TRPV1 (0.74) | TRPV1KDM4ENPC1RAB9AGALR3 | |
| SCHEMBL13181111 | 0.86 | TRPV1 (0.88) | TRPV1KDM4ENPC1RAB9AGALR3 | |
| SCHEMBL2915657 | 0.86 | TRPV1 (0.72) | TRPV1KDM4ENPC1RAB9AGALR3 | |
| SCHEMBL4611858 | 0.85 | TRPV1 (0.72) | TRPV1KDM4ENPC1RAB9AGALR3 | |
| SCHEMBL7302615 | 0.85 | NR1H4 (0.76) | TRPV1KDM4ENPC1RAB9AGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |