Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 4/20 | 0.84 |
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.79 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.79 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.79 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.79 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.79 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.79 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.79 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.79 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.79 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | VDR | P11473 | 2/20 | 0.78 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.69 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.69 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364729 | 1.00 | EPHA2 (0.84) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL4326984 | 1.00 | EPHA2 (0.84) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL25710302 | 0.91 | EPHA2 (0.76) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL23061517 | 0.90 | EPHA2 (0.80) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL25021694 | 0.89 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL5556804 | 0.89 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL16084677 | 0.89 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL25023120 | 0.89 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL22871921 | 0.89 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL25023044 | 0.89 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009052186-A1 | METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-04-23 | — | — | WO | disclosed |
| EP-0730869-B1 | BIODEGRADABLE MEDICINAL POLYMER ASSEMBLY WITH SUPERMOLECULAR STRUCTURE | YUI NOBUHIKO (JP) | 2001-06-27 | — | — | EP | disclosed |
| US-5855900-A | Supramolecular-structured biodegradable polymeric assembly for drug delivery | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0730869-A1 | BIODEGRADABLE MEDICINAL POLYMER ASSEMBLY WITH SUPERMOLECULAR STRUCTURE | Yui, Nobuhiko (JP) | 1996-09-11 | — | — | EP | disclosed |