Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841555 | 0.86 | BLM (0.47) | BLMESR1ESR2MEN1TSHR | |
| SCHEMBL4328760 | 0.85 | BLM (0.57) | BLMESR1ESR2MEN1TSHR | |
| SCHEMBL14477215 | 0.85 | PTPRB (0.47) | BLMESR1ESR2MEN1TSHR | |
| SCHEMBL17151908 | 0.85 | PTPRB (0.47) | BLMESR1ESR2MEN1TSHR | |
| SCHEMBL539520 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1RECQLLMNA | |
| SCHEMBL539519 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1RECQLLMNA | |
| SCHEMBL27500342 | 0.80 | ESR1 (0.44) | BLMESR1ESR2MEN1TSHR | |
| SCHEMBL24961601 | 0.79 | MIF (0.43) | BLMESR1ESR2MEN1TSHR | |
| SCHEMBL28928144 | 0.79 | MIF (0.43) | BLMESR1ESR2MEN1TSHR | |
| SCHEMBL3665931 | 0.78 | ESR1 (0.53) | BLMESR1ESR2MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |