Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 18/20 | 0.91 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365104 | 0.95 | FOLH1 (1.00) | FOLH1GAA | |
| SCHEMBL11977601 | 0.95 | FOLH1 (1.00) | FOLH1GAA | |
| SCHEMBL4327484 | 0.95 | FOLH1 (1.00) | FOLH1GAA | |
| SCHEMBL19756834 | 0.93 | FOLH1 (0.86) | FOLH1GAA | |
| SCHEMBL20335023 | 0.91 | FOLH1 (0.83) | FOLH1 | |
| SCHEMBL20335021 | 0.91 | FOLH1 (0.83) | FOLH1 | |
| SCHEMBL4328770 | 0.89 | FOLH1 (0.91) | FOLH1 | |
| SCHEMBL4326624 | 0.89 | FOLH1 (0.91) | FOLH1 | |
| SCHEMBL16654681 | 0.89 | FOLH1 (0.91) | FOLH1 | |
| SCHEMBL4338893 | 0.89 | FOLH1 (0.91) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097111-A2 | HETERODIMERS OF GLUTAMIC ACID | Molecular Insight Pharmaceuticals, Inc. (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008058192-A2 | HETERODIMERS OF GLUTAMIC ACID | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2008-05-15 | — | — | WO | disclosed |