Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325148 | 0.96 | TSHR (0.64) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL25431935 | 0.92 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28458416 | 0.87 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL22325553 | 0.87 | TSHR (0.68) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9875480 | 0.87 | TSHR (0.68) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9636788 | 0.85 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL3610833 | 0.84 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9155824 | 0.84 | TSHR (0.74) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL731737 | 0.83 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL10456655 | 0.82 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2130817-B1 | Polymerizable Type II photoinitiators and curable compositions | AGFA GRAPHICS NV (BE) | 2016-01-06 | — | — | EP | disclosed |
| US-8389769-B2 | Polymerizable type II photoinitiators and curable compositions | AGFA GRAPHICS NV (BE) | 2013-03-05 | — | — | US | disclosed |
| US-20110063388-A1 | POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2011-03-17 | — | — | US | disclosed |
| WO-2009147057-A1 | POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2009-12-10 | — | — | WO | disclosed |
| EP-2130817-A1 | Polymerizable Type II photoinitiators and curable compositions | AGFA Graphics NV (BE) | 2009-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110063388-A1 | POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS | CCNH, CRKL, ERH | TSHR 2470/4885ALDH1A1 1584/4885CYP3A4 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.