Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13577899 | 0.87 | CPT2 (0.37) | CPT2CPT1ACPT1BSCN9ALMNA | |
| SCHEMBL13577923 | 0.86 | CPT2 (0.47) | CPT2CPT1ACPT1BALDH1A1LMNA | |
| SCHEMBL4338970 | 0.85 | KMT2A (0.47) | CPT2CPT1ACPT1BSCN9AALDH1A1 | |
| SCHEMBL4334077 | 0.80 | CPT2 (0.42) | CPT2CPT1ACPT1BSCN9AALDH1A1 | |
| SCHEMBL13577921 | 0.80 | EGFR (0.36) | SCN9ALMNAMAPTL3MBTL1 | |
| SCHEMBL4335570 | 0.79 | CPT2 (0.52) | CPT2CPT1ACPT1BSCN9AALDH1A1 | |
| SCHEMBL4333770 | 0.79 | CPT2 (0.53) | CPT2CPT1ACPT1BSCN9AALDH1A1 | |
| SCHEMBL13578019 | 0.79 | ATM (0.49) | CPT2CPT1ACPT1BALDH1A1LMNA | |
| SCHEMBL4336040 | 0.78 | CPT2 (0.43) | CPT2CPT1ACPT1BSCN9AALDH1A1 | |
| SCHEMBL13577920 | 0.78 | KMT2A (0.46) | CPT2CPT1ACPT1BSCN9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | claimed |
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |